They’re best buddies, Hollywood-style. From Salma Hayek and Penélope Cruz to Ben Affleck and Matt Damon, these A-list pairs are enjoying life with a little help from their friends. While some met after hitting it big, like Vince Vaughn and his comical chum Owen Wilson, others like Jessica and Ashlee Simpson are bound by sisterly love. And still others found a pal in their stylist, like Rachel Zoe and her famous client/friend Nicole Richie. —Tracey Anderson
